harsh skill

---
name: harsh
description: complete a comprehensive and brutally honest critical review of your manuscript. The review identifies major methodological flaws and areas where the work falls short of publication standards for a high-impact clinical journal.
---

# Harsh

This command will complete a comprehensive and brutally honest critical review of your manuscript. The review identifies major methodological flaws and areas where the work falls short of publication standards for a high-impact clinical journal.

## When to use

- When preparing a manuscript for submission to a high-impact clinical journal
- When you need honest feedback about methodological weaknesses
- When you want to identify publication-blocking issues before submission
- When seeking to improve the scientific rigor of your work

## Instructions

- Read the README.md and CLAUDE.md to understand the project purpose, setup instructions, and key information
- Provide a concise overview of the project based on the gathered context
- Focus on ./result and ./manuscripts
- Save the harsh critical comment in the ./docs/
- Give a plan to fix the problem that will contributing meaningful biological insights